BDBM50362533 CHEMBL1941010

SMILES: Fc1ccc(cc1)C(=O)Cn1c(nc2ccccc12)-c1ccccn1

InChI Key: InChIKey=NOLNQMFTDAFHCP-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50362533   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Plasmepsin 2 (Plasmodium falciparum)	BDBM50362533 (CHEMBL1941010) Show SMILES Fc1ccc(cc1)C(=O)Cn1c(nc2ccccc12)-c1ccccn1 Show InChI InChI=1S/C20H14FN3O/c21-15-10-8-14(9-11-15)19(25)13-24-18-7-2-1-5-16(18)23-20(24)17-6-3-4-12-22-17/h1-12H,13H2	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum plasmepsin-2 using DABCYL-Glu-Arg-Nle-Phe-Leu-Ser-Phe-Pro-EDANS as substrate by FRET analysis				Bioorg Med Chem Lett 22: 1282-6 (2012) Article DOI: 10.1016/j.bmcl.2011.10.018 BindingDB Entry DOI: 10.7270/Q2WS8TPJ
					More data for this Ligand-Target Pair
beta-Glucuronidase (β-glucuronidase) (Homo sapiens (Human))	BDBM50362533 (CHEMBL1941010) Show SMILES Fc1ccc(cc1)C(=O)Cn1c(nc2ccccc12)-c1ccccn1 Show InChI InChI=1S/C20H14FN3O/c21-15-10-8-14(9-11-15)19(25)13-24-18-7-2-1-5-16(18)23-20(24)17-6-3-4-12-22-17/h1-12H,13H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.48E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of KwaZulu-Natal Curated by ChEMBL					Assay Description Inhibition of beta-glucuronidase (unknown origin)				Eur J Med Chem 187: (2020)
					More data for this Ligand-Target Pair
Cathepsin D (Homo sapiens (Human))	BDBM50362533 (CHEMBL1941010) Show SMILES Fc1ccc(cc1)C(=O)Cn1c(nc2ccccc12)-c1ccccn1 Show InChI InChI=1S/C20H14FN3O/c21-15-10-8-14(9-11-15)19(25)13-24-18-7-2-1-5-16(18)23-20(24)17-6-3-4-12-22-17/h1-12H,13H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.19E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of human cathepsin D using DABCYL-Glu-Arg-Nle-Phe-Leu-Ser-Phe-Pro-EDANS as substrate by FRET analysis				Bioorg Med Chem Lett 22: 1282-6 (2012) Article DOI: 10.1016/j.bmcl.2011.10.018 BindingDB Entry DOI: 10.7270/Q2WS8TPJ
					More data for this Ligand-Target Pair