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SMILES: CS(=O)(=O)c1ccc(CSc2nc(N)cc(=O)[nH]2)cc1

InChI Key: InChIKey=KCVOKCQFKUNNHZ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50362569   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))		BDBM50362569
PNG
(CHEMBL1938858)
Show SMILES CS(=O)(=O)c1ccc(CSc2nc(N)cc(=O)[nH]2)cc1
Show InChI InChI=1S/C12H13N3O3S2/c1-20(17,18)9-4-2-8(3-5-9)7-19-12-14-10(13)6-11(16)15-12/h2-6H,7H2,1H3,(H3,13,14,15,16)
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KEGG

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Similars
Article
PubMed
n/an/a>3.00E+4n/an/an/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Antagonist activity at 20% inactivated human sodium channel Nav1.7 expressed in human HEK293 cells by patch-clamp electrophysiological assay

Bioorg Med Chem Lett 22: 1055-60 (2012)


Article DOI: 10.1016/j.bmcl.2011.11.111
BindingDB Entry DOI: 10.7270/Q2CV4J7X
More data for this
Ligand-Target Pair