null

SMILES: CN(C)CCOc1cccc(c1)C1NC(=S)N=C2C1C(=O)c1ccccc21

InChI Key: InChIKey=UWCXUAJDHXYHCN-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50362765   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily A member 1 (Rattus norvegicus)	BDBM50362765 (CHEMBL1939834) Show SMILES CN(C)CCOc1cccc(c1)C1NC(=S)N=C2C1C(=O)c1ccccc21 |c:17| Show InChI InChI=1S/C21H21N3O2S/c1-24(2)10-11-26-14-7-5-6-13(12-14)18-17-19(23-21(27)22-18)15-8-3-4-9-16(15)20(17)25/h3-9,12,17-18H,10-11H2,1-2H3,(H,22,27)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research& Development, Janssen Pharmaceutica N.V. Curated by ChEMBL					Assay Description Antagonist activity at rat TRPA1 expressed in HEK293 cells assessed as inhibition of BITC-induced increase in intracellular calcium concentration by ...				Bioorg Med Chem Lett 22: 797-800 (2012) Article DOI: 10.1016/j.bmcl.2011.12.068 BindingDB Entry DOI: 10.7270/Q2736RC4
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1 (Homo sapiens (Human))	BDBM50362765 (CHEMBL1939834) Show SMILES CN(C)CCOc1cccc(c1)C1NC(=S)N=C2C1C(=O)c1ccccc21 |c:17| Show InChI InChI=1S/C21H21N3O2S/c1-24(2)10-11-26-14-7-5-6-13(12-14)18-17-19(23-21(27)22-18)15-8-3-4-9-16(15)20(17)25/h3-9,12,17-18H,10-11H2,1-2H3,(H,22,27)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research& Development, Janssen Pharmaceutica N.V. Curated by ChEMBL					Assay Description Antagonist activity at human TRPA1 expressed in HEK293 cells assessed as inhibition of 5H-dibenzo[b,e]azepine-10-carboxylic acid methyl ester-induced...				Bioorg Med Chem Lett 22: 797-800 (2012) Article DOI: 10.1016/j.bmcl.2011.12.068 BindingDB Entry DOI: 10.7270/Q2736RC4
					More data for this Ligand-Target Pair