null

SMILES: CN(C)CCCOc1cccc(c1)C1NC(=S)N=C2C1C(=O)c1ccccc21

InChI Key: InChIKey=XDJQQPBNBLIYAV-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50362766   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily A member 1 (Rattus norvegicus)	BDBM50362766 (CHEMBL1939830) Show SMILES CN(C)CCCOc1cccc(c1)C1NC(=S)N=C2C1C(=O)c1ccccc21 |c:18| Show InChI InChI=1S/C22H23N3O2S/c1-25(2)11-6-12-27-15-8-5-7-14(13-15)19-18-20(24-22(28)23-19)16-9-3-4-10-17(16)21(18)26/h3-5,7-10,13,18-19H,6,11-12H2,1-2H3,(H,23,28)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research& Development, Janssen Pharmaceutica N.V. Curated by ChEMBL					Assay Description Antagonist activity at rat TRPA1 expressed in HEK293 cells assessed as inhibition of BITC-induced increase in intracellular calcium concentration by ...				Bioorg Med Chem Lett 22: 797-800 (2012) Article DOI: 10.1016/j.bmcl.2011.12.068 BindingDB Entry DOI: 10.7270/Q2736RC4
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1 (Homo sapiens (Human))	BDBM50362766 (CHEMBL1939830) Show SMILES CN(C)CCCOc1cccc(c1)C1NC(=S)N=C2C1C(=O)c1ccccc21 |c:18| Show InChI InChI=1S/C22H23N3O2S/c1-25(2)11-6-12-27-15-8-5-7-14(13-15)19-18-20(24-22(28)23-19)16-9-3-4-10-17(16)21(18)26/h3-5,7-10,13,18-19H,6,11-12H2,1-2H3,(H,23,28)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research& Development, Janssen Pharmaceutica N.V. Curated by ChEMBL					Assay Description Antagonist activity at human TRPA1 expressed in HEK293 cells assessed as inhibition of 5H-dibenzo[b,e]azepine-10-carboxylic acid methyl ester-induced...				Bioorg Med Chem Lett 22: 797-800 (2012) Article DOI: 10.1016/j.bmcl.2011.12.068 BindingDB Entry DOI: 10.7270/Q2736RC4
					More data for this Ligand-Target Pair