BDBM50362935 CHEMBL1946131

SMILES: O=c1[nH]c2ncc(nc2n1CC1CCOCC1)-c1ccc(cc1)-n1cccn1

InChI Key: InChIKey=UYHJRNVVRSAPDJ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50362935   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM50362935 (CHEMBL1946131) Show SMILES O=c1[nH]c2ncc(nc2n1CC1CCOCC1)-c1ccc(cc1)-n1cccn1 Show InChI InChI=1S/C20H20N6O2/c27-20-24-18-19(25(20)13-14-6-10-28-11-7-14)23-17(12-21-18)15-2-4-16(5-3-15)26-9-1-8-22-26/h1-5,8-9,12,14H,6-7,10-11,13H2,(H,21,24,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Corporation Curated by ChEMBL					Assay Description Inhibition of mTOR				Bioorg Med Chem Lett 21: 6793-9 (2011) Article DOI: 10.1016/j.bmcl.2011.09.035 BindingDB Entry DOI: 10.7270/Q28W3DR1
					More data for this Ligand-Target Pair