BDBM50363023 CHEMBL1945818

SMILES: FC(F)(F)CCC(=O)N1CCC(CC1)c1nc(no1)-c1ccncc1

InChI Key: InChIKey=ZOUIZUIOMVHIKX-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50363023   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transcriptional repressor EthR (EthR) (Mycobacterium tuberculosis)	BDBM50363023 (CHEMBL1945818) Show SMILES FC(F)(F)CCC(=O)N1CCC(CC1)c1nc(no1)-c1ccncc1 Show InChI InChI=1S/C16H17F3N4O2/c17-16(18,19)6-1-13(24)23-9-4-12(5-10-23)15-21-14(22-25-15)11-2-7-20-8-3-11/h2-3,7-8,12H,1,4-6,9-10H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	9.30E+3	n/a	n/a	n/a	n/a
Universit£ Lille Nord de France Curated by ChEMBL					Assay Description Inhibition of Mycobacterium tuberculosis H37Rv EthR in Mycobacterium tuberculosis H37Rv expressing GFP infected mouse in RAW264.7 cells assessed as p...				J Med Chem 55: 68-83 (2012) Article DOI: 10.1021/jm200825u BindingDB Entry DOI: 10.7270/Q2RX9CJW
					More data for this Ligand-Target Pair