Found 3 hits for monomerid = 50363334 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50363334
(CHEMBL1946019)Show SMILES [#6]-[#6]-[#7](-[#6])-[#6](=O)-c1ccc(cc1)-[#6](=[#6]-1/[#6]-[#6]-[#7](-[#6]-c2ccc(F)cc2)-[#6]-[#6]-1)\c1ccccc1-[#7]-[#6](-[#6])=O Show InChI InChI=1S/C31H34FN3O2/c1-4-34(3)31(37)26-13-11-24(12-14-26)30(28-7-5-6-8-29(28)33-22(2)36)25-17-19-35(20-18-25)21-23-9-15-27(32)16-10-23/h5-16H,4,17-21H2,1-3H3,(H,33,36) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 0.450 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca Pharmaceuticals
Curated by ChEMBL
| Assay Description Displacement of radiolabeled iodinated deltorphin 2 from delta opioid receptor expressed in HEK293 cell membranes |
Bioorg Med Chem Lett 22: 1174-8 (2012)
Article DOI: 10.1016/j.bmcl.2011.11.089 BindingDB Entry DOI: 10.7270/Q2FF3STJ |
More data for this Ligand-Target Pair | |
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human)) | BDBM50363334
(CHEMBL1946019)Show SMILES [#6]-[#6]-[#7](-[#6])-[#6](=O)-c1ccc(cc1)-[#6](=[#6]-1/[#6]-[#6]-[#7](-[#6]-c2ccc(F)cc2)-[#6]-[#6]-1)\c1ccccc1-[#7]-[#6](-[#6])=O Show InChI InChI=1S/C31H34FN3O2/c1-4-34(3)31(37)26-13-11-24(12-14-26)30(28-7-5-6-8-29(28)33-22(2)36)25-17-19-35(20-18-25)21-23-9-15-27(32)16-10-23/h5-16H,4,17-21H2,1-3H3,(H,33,36) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca Pharmaceuticals
Curated by ChEMBL
| Assay Description Inhibition of human ERG |
Bioorg Med Chem Lett 22: 1174-8 (2012)
Article DOI: 10.1016/j.bmcl.2011.11.089 BindingDB Entry DOI: 10.7270/Q2FF3STJ |
More data for this Ligand-Target Pair | |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM50363334
(CHEMBL1946019)Show SMILES [#6]-[#6]-[#7](-[#6])-[#6](=O)-c1ccc(cc1)-[#6](=[#6]-1/[#6]-[#6]-[#7](-[#6]-c2ccc(F)cc2)-[#6]-[#6]-1)\c1ccccc1-[#7]-[#6](-[#6])=O Show InChI InChI=1S/C31H34FN3O2/c1-4-34(3)31(37)26-13-11-24(12-14-26)30(28-7-5-6-8-29(28)33-22(2)36)25-17-19-35(20-18-25)21-23-9-15-27(32)16-10-23/h5-16H,4,17-21H2,1-3H3,(H,33,36) | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 990 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca Pharmaceuticals
Curated by ChEMBL
| Assay Description Displacement of radiolabeled FK33-824 from mu opioid receptor expressed in HEK293 cell membranes |
Bioorg Med Chem Lett 22: 1174-8 (2012)
Article DOI: 10.1016/j.bmcl.2011.11.089 BindingDB Entry DOI: 10.7270/Q2FF3STJ |
More data for this Ligand-Target Pair | |