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SMILES: CC(CO)CN1CC(C)(C)[C@@H](Oc2ccc(C#N)c(c2)C(F)(F)F)C1=O

InChI Key: InChIKey=NVQOZVXQFSXRCW-MHTVFEQDSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50363359   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Androgen receptor


(Homo sapiens (Human))		BDBM50363359
PNG
(CHEMBL1947183)
Show SMILES CC(CO)CN1CC(C)(C)[C@@H](Oc2ccc(C#N)c(c2)C(F)(F)F)C1=O |r|
Show InChI InChI=1S/C18H21F3N2O3/c1-11(9-24)8-23-10-17(2,3)15(16(23)25)26-13-5-4-12(7-22)14(6-13)18(19,20)21/h4-6,11,15,24H,8-10H2,1-3H3/t11?,15-/m0/s1
PDB
MMDB

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Reactome pathway
KEGG

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PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 371n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Antagonist activity at androgen receptor expressed in human LNAR cells assessed as inhibition of R1881-induced luciferase activity by spectrophotomet...

Bioorg Med Chem Lett 22: 1230-6 (2012)


Article DOI: 10.1016/j.bmcl.2011.11.068
BindingDB Entry DOI: 10.7270/Q29S1RG3
More data for this
Ligand-Target Pair