BDBM50363435 CHEMBL1944783

SMILES: COCc1cc(CNC(=O)c2c3OC4=CC(=O)C(C(C)=O)C(=O)[C@@]4(C)c3c(O)cc2OC)c2ccccc2c1

InChI Key: InChIKey=ZNRXELADCRGVAX-BXFARTRRSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50363435   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor (Homo sapiens (Human))	BDBM50363435 (CHEMBL1944783) Show SMILES COCc1cc(CNC(=O)c2c3OC4=CC(=O)C(C(C)=O)C(=O)[C@@]4(C)c3c(O)cc2OC)c2ccccc2c1 |r,t:13| Show InChI InChI=1S/C30H27NO8/c1-15(32)24-20(33)12-23-30(2,28(24)35)26-21(34)11-22(38-4)25(27(26)39-23)29(36)31-13-18-10-16(14-37-3)9-17-7-5-6-8-19(17)18/h5-12,24,34H,13-14H2,1-4H3,(H,31,36)/t24?,30-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	200	n/a	n/a	n/a	n/a
Daiichi Sankyo Co., Ltd Curated by ChEMBL					Assay Description Partial agonist activity at human PPARgamma expressed in MG-63 cells by reporter gene-based transactivation assay				Bioorg Med Chem Lett 22: 1348-51 (2012) Article DOI: 10.1016/j.bmcl.2011.12.066 BindingDB Entry DOI: 10.7270/Q28S4QC5
					More data for this Ligand-Target Pair