BDBM50363633 CHEMBL1945916
SMILES: [O-][N+](=O)c1ccc(cc1)C(=O)Cn1cnc(c1)-c1ccccc1
InChI Key: InChIKey=VMOMLXIICNJLTN-UHFFFAOYSA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Nitric-oxide synthase, brain (Rattus norvegicus (rat)) | BDBM50363633 (CHEMBL1945916) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 4.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Catania Curated by ChEMBL | Assay Description Inhibition of rat recombinant nNOS expressed in baculovirus-infected Sf9 cells assessed as conversion of oxyhemoglobin to methemoglobin by UV spectro... | Eur J Med Chem 49: 118-26 (2012) Article DOI: 10.1016/j.ejmech.2012.01.002 BindingDB Entry DOI: 10.7270/Q2416XHC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nitric-oxide synthase, endothelial (Mus musculus) | BDBM50363633 (CHEMBL1945916) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 7.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Catania Curated by ChEMBL | Assay Description Inhibition of C57BL/6 mouse eNOS assessed as conversion of oxyhemoglobin to methemoglobin by UV spectrophotometer analysis | Eur J Med Chem 49: 118-26 (2012) Article DOI: 10.1016/j.ejmech.2012.01.002 BindingDB Entry DOI: 10.7270/Q2416XHC | |||||||||||
More data for this Ligand-Target Pair |