null

SMILES: COc1ccc(cc1)-c1cc2c([nH]1)C(=O)NCCC2=C1NC(N)=NC1=O

InChI Key: InChIKey=ZUTGBHKZCBYQAK-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50363647   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase Chk2 (Homo sapiens (Human))	BDBM50363647 (CHEMBL1947251) Show SMILES COc1ccc(cc1)-c1cc2c([nH]1)C(=O)NCCC2=C1NC(N)=NC1=O |w:18.19,c:25| Show InChI InChI=1S/C18H17N5O3/c1-26-10-4-2-9(3-5-10)13-8-12-11(14-17(25)23-18(19)22-14)6-7-20-16(24)15(12)21-13/h2-5,8,21H,6-7H2,1H3,(H,20,24)(H3,19,22,23,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Michigan State University Curated by ChEMBL					Assay Description Inhibition of human Chk2 using STK1 as substrate after 10 mins by HTRF assay				Bioorg Med Chem 20: 1475-81 (2012) Article DOI: 10.1016/j.bmc.2011.12.054 BindingDB Entry DOI: 10.7270/Q20865RK
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Chk1 (Homo sapiens (Human))	BDBM50363647 (CHEMBL1947251) Show SMILES COc1ccc(cc1)-c1cc2c([nH]1)C(=O)NCCC2=C1NC(N)=NC1=O |w:18.19,c:25| Show InChI InChI=1S/C18H17N5O3/c1-26-10-4-2-9(3-5-10)13-8-12-11(14-17(25)23-18(19)22-14)6-7-20-16(24)15(12)21-13/h2-5,8,21H,6-7H2,1H3,(H,20,24)(H3,19,22,23,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	867	n/a	n/a	n/a	n/a	n/a	n/a
Michigan State University Curated by ChEMBL					Assay Description Inhibition of human CHK1 using STK1 as substrate after 10 mins by HTRF assay				Bioorg Med Chem 20: 1475-81 (2012) Article DOI: 10.1016/j.bmc.2011.12.054 BindingDB Entry DOI: 10.7270/Q20865RK
					More data for this Ligand-Target Pair