BDBM50363691 CHEMBL1945776

SMILES: COc1cccc(c1)-c1ccc(NS(=O)(=O)c2ccc3ccccc3c2)cc1

InChI Key: InChIKey=IZTGCWUVEIKBPB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50363691   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM50363691 (CHEMBL1945776) Show SMILES COc1cccc(c1)-c1ccc(NS(=O)(=O)c2ccc3ccccc3c2)cc1 Show InChI InChI=1S/C23H19NO3S/c1-27-22-8-4-7-19(15-22)18-9-12-21(13-10-18)24-28(25,26)23-14-11-17-5-2-3-6-20(17)16-23/h2-16,24H,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp Curated by ChEMBL					Assay Description Inhibition of human uPA using pyroGlu-Gly-Arg-p-NA.HCl as substrate preincubated for 15 mins prior sustrate addition measured for 10 mins by spectrop...				Bioorg Med Chem 20: 1557-68 (2012) Article DOI: 10.1016/j.bmc.2011.12.040 BindingDB Entry DOI: 10.7270/Q2QR4XK1
					More data for this Ligand-Target Pair