BDBM50363757 CHEMBL1947081

SMILES: CC(=O)Oc1ccc(Cl)cc1C1OC(=NN1C(C)=O)c1ccc2OCCOc2c1

InChI Key: InChIKey=OXNCCJLMDNRIKS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50363757   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM50363757 (CHEMBL1947081) Show SMILES CC(=O)Oc1ccc(Cl)cc1C1OC(=NN1C(C)=O)c1ccc2OCCOc2c1 |c:14| Show InChI InChI=1S/C20H17ClN2O6/c1-11(24)23-20(15-10-14(21)4-6-16(15)28-12(2)25)29-19(22-23)13-3-5-17-18(9-13)27-8-7-26-17/h3-6,9-10,20H,7-8H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	980	n/a	n/a	n/a	n/a	n/a	n/a
Nanjing University Curated by ChEMBL					Assay Description Inhibition of PI3Kgamma after 4 hrs				Bioorg Med Chem 20: 1373-9 (2012) Article DOI: 10.1016/j.bmc.2012.01.023 BindingDB Entry DOI: 10.7270/Q2BK1CT8
					More data for this Ligand-Target Pair