BDBM50363912 CHEMBL1946936

SMILES: COc1ccc(C2=NNC(=O)CC2C)c2[nH]c(nc12)C(F)(F)F

InChI Key: InChIKey=LEPWMRXBYJXALY-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50363912   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50363912 (CHEMBL1946936) Show SMILES COc1ccc(C2=NNC(=O)CC2C)c2[nH]c(nc12)C(F)(F)F |t:6| Show InChI InChI=1S/C14H13F3N4O2/c1-6-5-9(22)20-21-10(6)7-3-4-8(23-2)12-11(7)18-13(19-12)14(15,16)17/h3-4,6H,5H2,1-2H3,(H,18,19)(H,20,22)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Kyorin Pharmaceutical Co. Ltd. Curated by ChEMBL					Assay Description Inhibition of human PDE4B catalytic domain				Bioorg Med Chem 20: 1644-58 (2012) Article DOI: 10.1016/j.bmc.2012.01.033 BindingDB Entry DOI: 10.7270/Q2DB829P
					More data for this Ligand-Target Pair
Phosphodiesterase 3 (PDE3) (Homo sapiens (Human))	BDBM50363912 (CHEMBL1946936) Show SMILES COc1ccc(C2=NNC(=O)CC2C)c2[nH]c(nc12)C(F)(F)F |t:6| Show InChI InChI=1S/C14H13F3N4O2/c1-6-5-9(22)20-21-10(6)7-3-4-8(23-2)12-11(7)18-13(19-12)14(15,16)17/h3-4,6H,5H2,1-2H3,(H,18,19)(H,20,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.22E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kyorin Pharmaceutical Co. Ltd. Curated by ChEMBL					Assay Description Inhibition of human PDE3A catalytic domain				Bioorg Med Chem 20: 1644-58 (2012) Article DOI: 10.1016/j.bmc.2012.01.033 BindingDB Entry DOI: 10.7270/Q2DB829P
					More data for this Ligand-Target Pair