Found 3 hits for monomerid = 50364102 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50364102
(CHEMBL1950928)Show SMILES CC(=O)N1CCC(Cn2c(nc3cc(ccc23)S(=O)(=O)C2CCCC2)C(C)(C)C)CC1 Show InChI InChI=1S/C24H35N3O3S/c1-17(28)26-13-11-18(12-14-26)16-27-22-10-9-20(31(29,30)19-7-5-6-8-19)15-21(22)25-23(27)24(2,3)4/h9-10,15,18-19H,5-8,11-14,16H2,1-4H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 3 | n/a | n/a | n/a | n/a |
Arena Pharmaceuticals
Curated by ChEMBL
| Assay Description Agonist activity at human CB2 receptor assessed as inhibition of forskolin-induced cAMP production preincubated for 15 mins followed by forskolin cha... |
Cell Chem Biol 56: 8224-56 (2013)
Article DOI: 10.1021/jm4005626 BindingDB Entry DOI: 10.7270/Q2B859M5 |
More data for this Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50364102
(CHEMBL1950928)Show SMILES CC(=O)N1CCC(Cn2c(nc3cc(ccc23)S(=O)(=O)C2CCCC2)C(C)(C)C)CC1 Show InChI InChI=1S/C24H35N3O3S/c1-17(28)26-13-11-18(12-14-26)16-27-22-10-9-20(31(29,30)19-7-5-6-8-19)15-21(22)25-23(27)24(2,3)4/h9-10,15,18-19H,5-8,11-14,16H2,1-4H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 3.20 | n/a | n/a | n/a | n/a |
Janssen Research& Development
Curated by ChEMBL
| Assay Description Agonist activity at human CB2 receptor |
Bioorg Med Chem Lett 22: 547-52 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.091 BindingDB Entry DOI: 10.7270/Q2JW8FBF |
More data for this Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50364102
(CHEMBL1950928)Show SMILES CC(=O)N1CCC(Cn2c(nc3cc(ccc23)S(=O)(=O)C2CCCC2)C(C)(C)C)CC1 Show InChI InChI=1S/C24H35N3O3S/c1-17(28)26-13-11-18(12-14-26)16-27-22-10-9-20(31(29,30)19-7-5-6-8-19)15-21(22)25-23(27)24(2,3)4/h9-10,15,18-19H,5-8,11-14,16H2,1-4H3 | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Janssen Research& Development
Curated by ChEMBL
| Assay Description Agonist activity at human CB1 receptor |
Bioorg Med Chem Lett 22: 547-52 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.091 BindingDB Entry DOI: 10.7270/Q2JW8FBF |
More data for this Ligand-Target Pair | |