BDBM50364410 CHEMBL1950480

SMILES: Fc1ccccc1-c1nc2ccc(nc2s1)C1(CC1)c1ccccc1

InChI Key: InChIKey=DCBBXRFSJCTLPY-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50364410   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sphingosine 1-phosphate receptor 3 (Homo sapiens (Human))	BDBM50364410 (CHEMBL1950480) Show SMILES Fc1ccccc1-c1nc2ccc(nc2s1)C1(CC1)c1ccccc1 Show InChI InChI=1S/C21H15FN2S/c22-16-9-5-4-8-15(16)19-23-17-10-11-18(24-20(17)25-19)21(12-13-21)14-6-2-1-3-7-14/h1-11H,12-13H2	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Agonist activity at human S1P3 receptor expressed in CHO cells coexpressing chimeric Gq/i5 G-protein assessed as Ca2+ release by FLIPR assay				Bioorg Med Chem Lett 22: 1779-83 (2012) Article DOI: 10.1016/j.bmcl.2011.12.073 BindingDB Entry DOI: 10.7270/Q23R0TBJ
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human))	BDBM50364410 (CHEMBL1950480) Show SMILES Fc1ccccc1-c1nc2ccc(nc2s1)C1(CC1)c1ccccc1 Show InChI InChI=1S/C21H15FN2S/c22-16-9-5-4-8-15(16)19-23-17-10-11-18(24-20(17)25-19)21(12-13-21)14-6-2-1-3-7-14/h1-11H,12-13H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	45	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Agonist activity at eGFP-tagged human S1P1 receptor expressed in U2OS cells assessed as receptor internalization after 1 hr by Hoechst dye-based micr...				Bioorg Med Chem Lett 22: 1779-83 (2012) Article DOI: 10.1016/j.bmcl.2011.12.073 BindingDB Entry DOI: 10.7270/Q23R0TBJ
					More data for this Ligand-Target Pair