BDBM50364545 CHEMBL1951015

SMILES: CC(C)OC(=O)N1CCC(CC1)Oc1ncnc(Nc2cccnc2C)c1C

InChI Key: InChIKey=ATSNUQSZCLQENO-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50364545   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
G-protein coupled receptor 119 (GPR119) (Homo sapiens (Human))	BDBM50364545 (CHEMBL1951015) Show SMILES CC(C)OC(=O)N1CCC(CC1)Oc1ncnc(Nc2cccnc2C)c1C Show InChI InChI=1S/C20H27N5O3/c1-13(2)27-20(26)25-10-7-16(8-11-25)28-19-14(3)18(22-12-23-19)24-17-6-5-9-21-15(17)4/h5-6,9,12-13,16H,7-8,10-11H2,1-4H3,(H,22,23,24)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	92	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at human GPR119 receptor assessed as cAMP production by HTRF assay				Bioorg Med Chem Lett 22: 1750-5 (2012) Article DOI: 10.1016/j.bmcl.2011.12.092 BindingDB Entry DOI: 10.7270/Q26H4HW1
					More data for this Ligand-Target Pair
Glucose-dependent insulinotropic receptor (Rattus norvegicus)	BDBM50364545 (CHEMBL1951015) Show SMILES CC(C)OC(=O)N1CCC(CC1)Oc1ncnc(Nc2cccnc2C)c1C Show InChI InChI=1S/C20H27N5O3/c1-13(2)27-20(26)25-10-7-16(8-11-25)28-19-14(3)18(22-12-23-19)24-17-6-5-9-21-15(17)4/h5-6,9,12-13,16H,7-8,10-11H2,1-4H3,(H,22,23,24)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	700	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at rat GPR119 receptor assessed as cAMP production by HTRF assay				Bioorg Med Chem Lett 22: 1750-5 (2012) Article DOI: 10.1016/j.bmcl.2011.12.092 BindingDB Entry DOI: 10.7270/Q26H4HW1
					More data for this Ligand-Target Pair