BDBM50364619 CHEMBL1951315
SMILES: CCc1cc(CN2CC(C2)C(O)=O)sc1-c1noc(n1)-c1ccc(Oc2ccccc2C(C)C)cc1
InChI Key: InChIKey=YMRRPAIETNTXMA-UHFFFAOYSA-N
Data: 2 EC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sphingosine 1-phosphate receptor 3 (Homo sapiens (Human)) | BDBM50364619 (CHEMBL1951315) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.10E+4 | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd Curated by ChEMBL | Assay Description Agonist activity at human S1P3 receptor assessed as stimulation of [35S]GTPgamma binding | Bioorg Med Chem Lett 22: 1788-92 (2012) Article DOI: 10.1016/j.bmcl.2011.12.019 BindingDB Entry DOI: 10.7270/Q2Z038MT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human)) | BDBM50364619 (CHEMBL1951315) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 4.5 | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd Curated by ChEMBL | Assay Description Agonist activity at human S1P1 receptor assessed as stimulation of [35S]GTPgamma binding | Bioorg Med Chem Lett 22: 1788-92 (2012) Article DOI: 10.1016/j.bmcl.2011.12.019 BindingDB Entry DOI: 10.7270/Q2Z038MT | |||||||||||
More data for this Ligand-Target Pair |