BDBM50364732 CHEMBL1951671

SMILES: COc1cccc(c1)-n1ccc2c3c(OC)ccnc3sc2c1=O

InChI Key: InChIKey=XVDOLQADSKHXGB-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50364732   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor (RAT)	BDBM50364732 (CHEMBL1951671) Show SMILES COc1cccc(c1)-n1ccc2c3c(OC)ccnc3sc2c1=O Show InChI InChI=1S/C18H14N2O3S/c1-22-12-5-3-4-11(10-12)20-9-7-13-15-14(23-2)6-8-19-17(15)24-16(13)18(20)21/h3-10H,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	566	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Antagonist activity at rat metabotropic glutamate receptor 1				Bioorg Med Chem Lett 22: 1575-8 (2012) Article DOI: 10.1016/j.bmcl.2011.12.131 BindingDB Entry DOI: 10.7270/Q2F19063
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM50364732 (CHEMBL1951671) Show SMILES COc1cccc(c1)-n1ccc2c3c(OC)ccnc3sc2c1=O Show InChI InChI=1S/C18H14N2O3S/c1-22-12-5-3-4-11(10-12)20-9-7-13-15-14(23-2)6-8-19-17(15)24-16(13)18(20)21/h3-10H,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	118	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Antagonist activity at human metabotropic glutamate receptor 1				Bioorg Med Chem Lett 22: 1575-8 (2012) Article DOI: 10.1016/j.bmcl.2011.12.131 BindingDB Entry DOI: 10.7270/Q2F19063
					More data for this Ligand-Target Pair