null

SMILES: COc1ccnc2sc3c(ccn(C4CCCCC4)c3=O)c12

InChI Key: InChIKey=LQXNPVCHVQPXOM-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50364738   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 1 (RAT)	BDBM50364738 (CHEMBL1951677) Show SMILES COc1ccnc2sc3c(ccn(C4CCCCC4)c3=O)c12 Show InChI InChI=1S/C17H18N2O2S/c1-21-13-7-9-18-16-14(13)12-8-10-19(17(20)15(12)22-16)11-5-3-2-4-6-11/h7-11H,2-6H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Antagonist activity at rat metabotropic glutamate receptor 1				Bioorg Med Chem Lett 22: 1575-8 (2012) Article DOI: 10.1016/j.bmcl.2011.12.131 BindingDB Entry DOI: 10.7270/Q2F19063
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM50364738 (CHEMBL1951677) Show SMILES COc1ccnc2sc3c(ccn(C4CCCCC4)c3=O)c12 Show InChI InChI=1S/C17H18N2O2S/c1-21-13-7-9-18-16-14(13)12-8-10-19(17(20)15(12)22-16)11-5-3-2-4-6-11/h7-11H,2-6H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.40	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Antagonist activity at human metabotropic glutamate receptor 1				Bioorg Med Chem Lett 22: 1575-8 (2012) Article DOI: 10.1016/j.bmcl.2011.12.131 BindingDB Entry DOI: 10.7270/Q2F19063
					More data for this Ligand-Target Pair