BDBM50365040 CHEMBL1950917

SMILES: C[C@H](Nc1cc(ncn1)N1CCCC(C1)N1CCc2c(C1)cccc2-c1cccnc1)c1ccc(Cl)cc1

InChI Key: InChIKey=FJAVFDVEPOTXLF-YMQLSTQVSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50365040   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prolylcarboxypeptidase (PRCP) (Homo sapiens (Human))	BDBM50365040 (CHEMBL1950917) Show SMILES C[C@H](Nc1cc(ncn1)N1CCCC(C1)N1CCc2c(C1)cccc2-c1cccnc1)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C31H33ClN6/c1-22(23-9-11-26(32)12-10-23)36-30-17-31(35-21-34-30)38-15-4-7-27(20-38)37-16-13-29-25(19-37)5-2-8-28(29)24-6-3-14-33-18-24/h2-3,5-6,8-12,14,17-18,21-22,27H,4,7,13,15-16,19-20H2,1H3,(H,34,35,36)/t22-,27?/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human recombinant PrCP using Mca-Ala-Pro-Lys(Dnp)-OH as substrate after 30 mins by fluorescence analysis				Bioorg Med Chem Lett 22: 1727-30 (2012) Article DOI: 10.1016/j.bmcl.2011.12.098 BindingDB Entry DOI: 10.7270/Q2GT5NNH
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