BDBM50365058 CHEMBL1951067

SMILES: COc1ccc(cc1OC)C1=NN(CCCCNC[C@H](O)c2ccc(O)c(NC=O)c2)C(=O)C2CCCCC12

InChI Key: InChIKey=CYDUYTLCMWZTJY-OWWUNANSSA-N

Data: 1 IC50  1 Kd  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50365058   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50365058 (CHEMBL1951067) Show SMILES COc1ccc(cc1OC)C1=NN(CCCCNC[C@H](O)c2ccc(O)c(NC=O)c2)C(=O)C2CCCCC12 |r,t:11| Show InChI InChI=1S/C29H38N4O6/c1-38-26-12-10-20(16-27(26)39-2)28-21-7-3-4-8-22(21)29(37)33(32-28)14-6-5-13-30-17-25(36)19-9-11-24(35)23(15-19)31-18-34/h9-12,15-16,18,21-22,25,30,35-36H,3-8,13-14,17H2,1-2H3,(H,31,34)/t21?,22?,25-/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	265	n/a	n/a	n/a	n/a	n/a	n/a
Sun Yat-sen University Curated by ChEMBL					Assay Description Inhibition of human recombinant PDE4B2-mediated cAMP hydrolysis for 30 mins by colorimetric assay				Bioorg Med Chem Lett 22: 1523-6 (2012) Article DOI: 10.1016/j.bmcl.2012.01.013 BindingDB Entry DOI: 10.7270/Q2794548
					More data for this Ligand-Target Pair
Beta-2 adrenergic receptor (GUINEA PIG)	BDBM50365058 (CHEMBL1951067) Show SMILES COc1ccc(cc1OC)C1=NN(CCCCNC[C@H](O)c2ccc(O)c(NC=O)c2)C(=O)C2CCCCC12 |r,t:11| Show InChI InChI=1S/C29H38N4O6/c1-38-26-12-10-20(16-27(26)39-2)28-21-7-3-4-8-22(21)29(37)33(32-28)14-6-5-13-30-17-25(36)19-9-11-24(35)23(15-19)31-18-34/h9-12,15-16,18,21-22,25,30,35-36H,3-8,13-14,17H2,1-2H3,(H,31,34)/t21?,22?,25-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	0.708	n/a	n/a	n/a	n/a	n/a
Sun Yat-sen University Curated by ChEMBL					Assay Description Competitive antagonist activity at beta2-adrenoreceptor in guinea pig tracheal ring in the presence of N-(5-((1R)-2-(4-(4-(3,4-dimethoxyphenol)-1-oxo...				Bioorg Med Chem Lett 22: 1523-6 (2012) Article DOI: 10.1016/j.bmcl.2012.01.013 BindingDB Entry DOI: 10.7270/Q2794548
					More data for this Ligand-Target Pair
Beta-2 adrenergic receptor (GUINEA PIG)	BDBM50365058 (CHEMBL1951067) Show SMILES COc1ccc(cc1OC)C1=NN(CCCCNC[C@H](O)c2ccc(O)c(NC=O)c2)C(=O)C2CCCCC12 |r,t:11| Show InChI InChI=1S/C29H38N4O6/c1-38-26-12-10-20(16-27(26)39-2)28-21-7-3-4-8-22(21)29(37)33(32-28)14-6-5-13-30-17-25(36)19-9-11-24(35)23(15-19)31-18-34/h9-12,15-16,18,21-22,25,30,35-36H,3-8,13-14,17H2,1-2H3,(H,31,34)/t21?,22?,25-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.100	n/a	n/a	n/a	n/a
Sun Yat-sen University Curated by ChEMBL					Assay Description Agonist activity at beta2 adrenoceptor in guinea pig assessed as relaxation of histamine-induced tracheal ring contraction				Bioorg Med Chem Lett 22: 1523-6 (2012) Article DOI: 10.1016/j.bmcl.2012.01.013 BindingDB Entry DOI: 10.7270/Q2794548
					More data for this Ligand-Target Pair