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SMILES: COC(=O)c1ccccc1CNS(=O)(=O)c1cc(NC(C)=O)c(OC)cc1OC

InChI Key: InChIKey=PZYFKJRPNGVDHR-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50365090   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Bifunctional protein GlmU


(Streptococcus pneumoniae)		BDBM50365090
PNG
(CHEMBL1951179)
Show SMILES COC(=O)c1ccccc1CNS(=O)(=O)c1cc(NC(C)=O)c(OC)cc1OC
Show InChI InChI=1S/C19H22N2O7S/c1-12(22)21-15-9-18(17(27-3)10-16(15)26-2)29(24,25)20-11-13-7-5-6-8-14(13)19(23)28-4/h5-10,20H,11H2,1-4H3,(H,21,22)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>2.00E+5n/an/an/an/an/an/a



AstraZeneca R&D Boston

Curated by ChEMBL


Assay Description
Inhibition of Streptococcus pneumoniae acetyltransferase activity of GlmU using acetyl-CoA and glucosamine-1-phosphate after 30 mins by Ellman's meth...

Bioorg Med Chem Lett 22: 1510-9 (2012)


Article DOI: 10.1016/j.bmcl.2012.01.016
BindingDB Entry DOI: 10.7270/Q23J3DF0
More data for this
Ligand-Target Pair