null

SMILES: OC(=O)Cc1c([nH]c2cc(Cl)ccc12)C(=O)c1cc2CCCCc2cn1

InChI Key: InChIKey=CKTUGDQFDNCZCX-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50365168   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin G/H synthase 1 (Homo sapiens (Human))	BDBM50365168 (CHEMBL1950020) Show SMILES OC(=O)Cc1c([nH]c2cc(Cl)ccc12)C(=O)c1cc2CCCCc2cn1 Show InChI InChI=1S/C20H17ClN2O3/c21-13-5-6-14-15(9-18(24)25)19(23-16(14)8-13)20(26)17-7-11-3-1-2-4-12(11)10-22-17/h5-8,10,23H,1-4,9H2,(H,24,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of COX-1-mediated TXB2 production in human whole blood after 15 mins post A23187 stimulation by RIA				Eur J Med Chem 50: 179-95 (2012) Article DOI: 10.1016/j.ejmech.2012.01.053 BindingDB Entry DOI: 10.7270/Q2B27VR8
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50365168 (CHEMBL1950020) Show SMILES OC(=O)Cc1c([nH]c2cc(Cl)ccc12)C(=O)c1cc2CCCCc2cn1 Show InChI InChI=1S/C20H17ClN2O3/c21-13-5-6-14-15(9-18(24)25)19(23-16(14)8-13)20(26)17-7-11-3-1-2-4-12(11)10-22-17/h5-8,10,23H,1-4,9H2,(H,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of COX-2-mediated 6-keto-PGF1alpha production in IL-1beta-induced HUVEC preincubated for 20 mins prior A23187 stimulation measured after 1...				Eur J Med Chem 50: 179-95 (2012) Article DOI: 10.1016/j.ejmech.2012.01.053 BindingDB Entry DOI: 10.7270/Q2B27VR8
					More data for this Ligand-Target Pair