BDBM50365515 CHEMBL1957506
SMILES: CN(C)CCNC(=O)c1cn2cc(nc(N3CCOCC3)c2n1)-c1cccc2[nH]ncc12
InChI Key: InChIKey=PKDDPYVEJSWSNT-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
p110α/p85α (Homo sapiens (Human)) | BDBM50365515 (CHEMBL1957506) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 35 | n/a | n/a | n/a | n/a | n/a | n/a |
Spanish National Cancer Research Centre (CNIO). C/Melchor Fern£ndez Almagro 3 Curated by ChEMBL | Assay Description Inhibition of PI3K p110alpha/p85alpha | Bioorg Med Chem Lett 22: 1874-8 (2012) Article DOI: 10.1016/j.bmcl.2012.01.074 BindingDB Entry DOI: 10.7270/Q29Z95DX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
p110α/p85α (Homo sapiens (Human)) | BDBM50365515 (CHEMBL1957506) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 976 | n/a | n/a | n/a | n/a |
Spanish National Cancer Research Centre (CNIO). C/Melchor Fern£ndez Almagro 3 Curated by ChEMBL | Assay Description Inhibition of PI3K p110alpha/p85alpha-mediated AKT1 phosphorylation at Ser473 in human U2OS cells | Bioorg Med Chem Lett 22: 1874-8 (2012) Article DOI: 10.1016/j.bmcl.2012.01.074 BindingDB Entry DOI: 10.7270/Q29Z95DX | |||||||||||
More data for this Ligand-Target Pair |