BDBM50365587 CHEMBL1957820
SMILES: Fc1ccc(CCN2CCN(CC2)C(=O)c2cc(Br)cn3ccnc23)c(F)c1
InChI Key: InChIKey=CGLUZTJNYKGOLE-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50365587 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human)) | BDBM50365587
(CHEMBL1957820)Show SMILES Fc1ccc(CCN2CCN(CC2)C(=O)c2cc(Br)cn3ccnc23)c(F)c1 Show InChI InChI=1S/C20H19BrF2N4O/c21-15-11-17(19-24-4-6-27(19)13-15)20(28)26-9-7-25(8-10-26)5-3-14-1-2-16(22)12-18(14)23/h1-2,4,6,11-13H,3,5,7-10H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Arena Pharmaceuticals Inc.
Curated by ChEMBL
| Assay Description Displacement of [125I]-DOI from recombinant human 5HT2A receptor |
Bioorg Med Chem Lett 22: 1870-3 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.080 BindingDB Entry DOI: 10.7270/Q2XP75D0 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2C
(Homo sapiens (Human)) | BDBM50365587
(CHEMBL1957820)Show SMILES Fc1ccc(CCN2CCN(CC2)C(=O)c2cc(Br)cn3ccnc23)c(F)c1 Show InChI InChI=1S/C20H19BrF2N4O/c21-15-11-17(19-24-4-6-27(19)13-15)20(28)26-9-7-25(8-10-26)5-3-14-1-2-16(22)12-18(14)23/h1-2,4,6,11-13H,3,5,7-10H2 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 474 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Arena Pharmaceuticals Inc.
Curated by ChEMBL
| Assay Description Displacement of [125I]-DOI from recombinant human 5HT2C receptor |
Bioorg Med Chem Lett 22: 1870-3 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.080 BindingDB Entry DOI: 10.7270/Q2XP75D0 |
More data for this Ligand-Target Pair | |