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SMILES: C1CCN(CC1)C1CCN(CC1)c1nc2ncc(cc2o1)-c1cccc2ccnn12

InChI Key: InChIKey=NUJOTGYKFPUQJP-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50365656   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histamine H3 receptor


(Homo sapiens (Human))		BDBM50365656
PNG
(CHEMBL1958177)
Show SMILES C1CCN(CC1)C1CCN(CC1)c1nc2ncc(cc2o1)-c1cccc2ccnn12
Show InChI InChI=1S/C23H26N6O/c1-2-11-27(12-3-1)18-8-13-28(14-9-18)23-26-22-21(30-23)15-17(16-24-22)20-6-4-5-19-7-10-25-29(19)20/h4-7,10,15-16,18H,1-3,8-9,11-14H2
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 4n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]-N-alpha-methylhistamine from human recombinant histamine H3 receptor expressed in HEK cell membrane after 30 mins by Scintillati...

Bioorg Med Chem Lett 22: 2075-8 (2012)


Article DOI: 10.1016/j.bmcl.2012.01.020
BindingDB Entry DOI: 10.7270/Q2JH3MP9
More data for this
Ligand-Target Pair