BDBM50365703 CHEMBL1958417
SMILES: CN1CCC(CC1)Nc1nc(cc(=O)[nH]1)-c1c[nH]c2ncccc12
InChI Key: InChIKey=QYXQYZTXEISTSA-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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CDC7 and DBF4 (Homo sapiens (Human)) | BDBM50365703 (CHEMBL1958417) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.110 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Inhibition of human CDC7/DBF4 expressed using baculovirus expression system assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by ... | Bioorg Med Chem Lett 22: 1940-3 (2012) Article DOI: 10.1016/j.bmcl.2012.01.041 BindingDB Entry DOI: 10.7270/Q2DR2W0F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
CDC7 and DBF4 (Homo sapiens (Human)) | BDBM50365703 (CHEMBL1958417) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 2.61E+3 | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Inhibition of CDC7/DBF4-mediated MCM2 phosphorylation in human HCT116 cells after 6 hrs by spectrophotometric analysis | Bioorg Med Chem Lett 22: 1940-3 (2012) Article DOI: 10.1016/j.bmcl.2012.01.041 BindingDB Entry DOI: 10.7270/Q2DR2W0F | |||||||||||
More data for this Ligand-Target Pair |