BindingDB logo
myBDB logout

null

SMILES: CN(c1ccc(cc1)N1CCOCC1)c1ncc(-c2cn[nH]c2)n2ccnc12

InChI Key: InChIKey=LKDKLEVJIHSSPG-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50365783   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
MAP kinase-activated protein kinase 5


(Homo sapiens (Human))		BDBM50365783
PNG
(CHEMBL1956562)
Show SMILES CN(c1ccc(cc1)N1CCOCC1)c1ncc(-c2cn[nH]c2)n2ccnc12
Show InChI InChI=1S/C20H21N7O/c1-25(16-2-4-17(5-3-16)26-8-10-28-11-9-26)19-20-21-6-7-27(20)18(14-22-19)15-12-23-24-13-15/h2-7,12-14H,8-11H2,1H3,(H,23,24)
NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Galapagos NV

Curated by ChEMBL


Assay Description
Inhibition of MAPKAPK5

Bioorg Med Chem Lett 22: 2266-70 (2012)


Article DOI: 10.1016/j.bmcl.2012.01.077
BindingDB Entry DOI: 10.7270/Q2CR5TT6
More data for this
Ligand-Target Pair