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BDBM50365832 CHEMBL1957011

SMILES: CC(C)N1CCC[C@H](Cn2c(C)nc3ncc(Oc4ccc5n(C)cnc5c4)nc3c2=O)C1

InChI Key: InChIKey=LDGXZHKIWMVOAM-KRWDZBQOSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50365832   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Ghrelin receptor


(Homo sapiens (Human))		BDBM50365832
PNG
(CHEMBL1957011)
Show SMILES CC(C)N1CCC[C@H](Cn2c(C)nc3ncc(Oc4ccc5n(C)cnc5c4)nc3c2=O)C1 |r|
Show InChI InChI=1S/C24H29N7O2/c1-15(2)30-9-5-6-17(12-30)13-31-16(3)27-23-22(24(31)32)28-21(11-25-23)33-18-7-8-20-19(10-18)26-14-29(20)4/h7-8,10-11,14-15,17H,5-6,9,12-13H2,1-4H3/t17-/m0/s1
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PubMed
 5n/an/an/an/an/an/an/an/a



Prosidion Ltd

Curated by ChEMBL


Assay Description
Displacement of [125I]-Ghrelin from human GHSR membranes overexpressing GSH-R1a by scintillation counting

Bioorg Med Chem Lett 22: 2271-8 (2012)


Article DOI: 10.1016/j.bmcl.2012.01.078
BindingDB Entry DOI: 10.7270/Q20G3KMP
More data for this
Ligand-Target Pair