null

SMILES: Oc1csc(n1)N1N=C(CC1c1ccc(F)cc1)c1ccc(Br)cc1

InChI Key: InChIKey=CIIDMOCYZAQMCR-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50365932   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50365932 (CHEMBL1958038) Show SMILES Oc1csc(n1)N1N=C(CC1c1ccc(F)cc1)c1ccc(Br)cc1 |c:8| Show InChI InChI=1S/C18H13BrFN3OS/c19-13-5-1-11(2-6-13)15-9-16(12-3-7-14(20)8-4-12)23(22-15)18-21-17(24)10-25-18/h1-8,10,16,24H,9H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.48E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nanjing University Curated by ChEMBL					Assay Description Inhibition of histidine-tagged human recombinant cytoplasmic domain of EGFR expressed in baculovirus infected insect Sf9 cells after 1 hr by DELFIA/t...				Bioorg Med Chem 20: 2010-8 (2012) Article DOI: 10.1016/j.bmc.2012.01.051 BindingDB Entry DOI: 10.7270/Q27081WW
					More data for this Ligand-Target Pair
Receptor tyrosine-protein kinase erbB-2 (Homo sapiens (Human))	BDBM50365932 (CHEMBL1958038) Show SMILES Oc1csc(n1)N1N=C(CC1c1ccc(F)cc1)c1ccc(Br)cc1 |c:8| Show InChI InChI=1S/C18H13BrFN3OS/c19-13-5-1-11(2-6-13)15-9-16(12-3-7-14(20)8-4-12)23(22-15)18-21-17(24)10-25-18/h1-8,10,16,24H,9H2	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.14E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nanjing University Curated by ChEMBL					Assay Description Inhibition of histidine-tagged human recombinant cytoplasmic domain of HER2 expressed in baculovirus infected insect Sf9 cells after 1 hr by DELFIA/t...				Bioorg Med Chem 20: 2010-8 (2012) Article DOI: 10.1016/j.bmc.2012.01.051 BindingDB Entry DOI: 10.7270/Q27081WW
					More data for this Ligand-Target Pair