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SMILES: OS(O)(=O)=O.Nc1ncnc2n(cnc12)[C@@H]1O[C@H](CS[C@H]2CN[C@@H](C2)C(O)=O)[C@@H](O)[C@H]1O

InChI Key: InChIKey=MEKRNVYIIASAEQ-PWAUXLQOSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50366316   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
S-adenosylmethionine decarboxylase proenzyme


(Homo sapiens (Human))		BDBM50366316
PNG
(CHEMBL3392209 | CHEMBL605267)
Show SMILES OS(O)(=O)=O.Nc1ncnc2n(cnc12)[C@@H]1O[C@H](CS[C@H]2CN[C@@H](C2)C(O)=O)[C@@H](O)[C@H]1O |r|
Show InChI InChI=1S/C15H20N6O5S/c16-12-9-13(19-4-18-12)21(5-20-9)14-11(23)10(22)8(26-14)3-27-6-1-7(15(24)25)17-2-6/h4-8,10-11,14,17,22-23H,1-3H2,(H,24,25)(H2,16,18,19)/t6-,7-,8+,10+,11+,14?/m0/s1
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Similars
Article
 9.60E+5n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Tested for irreversible inhibitory activity against AdoMet-DC (S-adenosyl-methionine decarboxylase-) isolated from Escherichia coli

Bioorg Med Chem Lett 3: 147-152 (1993)


Article DOI: 10.1016/S0960-894X(01)80865-9
BindingDB Entry DOI: 10.7270/Q2PR7WG3
More data for this
Ligand-Target Pair