BindingDB PrimarySearch

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SMILES: N[C@@H]([C@H](OCC1CCCCC1)C(O)=O)C(O)=O

InChI Key: InChIKey=FKSWJLRIKQYTFH-IUCAKERBSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50366637
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Excitatory amino acid transporter 3 (Homo sapiens (Human))	BDBM50366637 (CHEMBL4164207) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Groningen Curated by ChEMBL					Assay Description Inhibition of human EAAT3 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting method				J Med Chem 61: 7741-7753 (2018) Article DOI: 10.1021/acs.jmedchem.8b00700 BindingDB Entry DOI: 10.7270/Q2G44ST4
University of Groningen Curated by ChEMBL					More data for this Ligand-Target Pair
Excitatory amino acid transporter 2 (Homo sapiens (Human))	BDBM50366637 (CHEMBL4164207) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	490	n/a	n/a	n/a	n/a	n/a	n/a
University of Groningen Curated by ChEMBL					Assay Description Inhibition of human EAAT2 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting method				J Med Chem 61: 7741-7753 (2018) Article DOI: 10.1021/acs.jmedchem.8b00700 BindingDB Entry DOI: 10.7270/Q2G44ST4
University of Groningen Curated by ChEMBL					More data for this Ligand-Target Pair
Excitatory amino acid transporter 1 (Homo sapiens (Human))	BDBM50366637 (CHEMBL4164207) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	620	n/a	n/a	n/a	n/a	n/a	n/a
University of Groningen Curated by ChEMBL					Assay Description Inhibition of human EAAT1 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting method				J Med Chem 61: 7741-7753 (2018) Article DOI: 10.1021/acs.jmedchem.8b00700 BindingDB Entry DOI: 10.7270/Q2G44ST4
University of Groningen Curated by ChEMBL					More data for this Ligand-Target Pair
Excitatory amino acid transporter 2 (Homo sapiens (Human))	BDBM50366637 (CHEMBL4164207) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	490	n/a	n/a	n/a	n/a	n/a	n/a
University of Groningen Curated by ChEMBL					Assay Description Inhibition of human EAAT2 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting method				J Med Chem 61: 7741-7753 (2018) Article DOI: 10.1021/acs.jmedchem.8b00700 BindingDB Entry DOI: 10.7270/Q2G44ST4
University of Groningen Curated by ChEMBL					More data for this Ligand-Target Pair
Excitatory amino acid transporter 4 (Rattus norvegicus)	BDBM50366637 (CHEMBL4164207) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Groningen Curated by ChEMBL					Assay Description Inhibition of rat EAAT4 expressed in tsA201 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting method				J Med Chem 61: 7741-7753 (2018) Article DOI: 10.1021/acs.jmedchem.8b00700 BindingDB Entry DOI: 10.7270/Q2G44ST4
University of Groningen Curated by ChEMBL					More data for this Ligand-Target Pair
Excitatory amino acid transporter 1 (Homo sapiens (Human))	BDBM50366637 (CHEMBL4164207) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	631	n/a	n/a	n/a	n/a	n/a	n/a
University of Groningen Curated by ChEMBL					Assay Description Inhibition of human EAAT1 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting method				J Med Chem 61: 7741-7753 (2018) Article DOI: 10.1021/acs.jmedchem.8b00700 BindingDB Entry DOI: 10.7270/Q2G44ST4
University of Groningen Curated by ChEMBL					More data for this Ligand-Target Pair
Excitatory amino acid transporter 3 (Homo sapiens (Human))	BDBM50366637 (CHEMBL4164207) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.57E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Groningen Curated by ChEMBL					Assay Description Inhibition of human EAAT3 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting method				J Med Chem 61: 7741-7753 (2018) Article DOI: 10.1021/acs.jmedchem.8b00700 BindingDB Entry DOI: 10.7270/Q2G44ST4
University of Groningen Curated by ChEMBL					More data for this Ligand-Target Pair
Excitatory amino acid transporter 4 (Rattus norvegicus)	BDBM50366637 (CHEMBL4164207) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.62E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Groningen Curated by ChEMBL					Assay Description Inhibition of rat EAAT4 expressed in tsA201 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting method				J Med Chem 61: 7741-7753 (2018) Article DOI: 10.1021/acs.jmedchem.8b00700 BindingDB Entry DOI: 10.7270/Q2G44ST4
University of Groningen Curated by ChEMBL					More data for this Ligand-Target Pair