null
SMILES: Nc1ncnc2n([C@@H]3O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O)c(NCCCCCCNC(=O)CI)nc12
InChI Key: InChIKey=PPOPDFOCXKHEPV-NVONZOAYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Adenylate kinase 2, mitochondrial (Rattus norvegicus) | BDBM50367068![]() (CHEMBL3350524 | CHEMBL609795) | PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet ![]() | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | 3.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Ability to inhibit rat adenylate kinase II, activity expressed as Inhibition constant | J Med Chem 25: 382-6 (1982) BindingDB Entry DOI: 10.7270/Q24F1R9V | |||||||||||
More data for this Ligand-Target Pair |