BDBM50367305 CHEMBL1791430
SMILES: CC(OP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12
InChI Key: InChIKey=DCRRZRVLEHSTSZ-ONBHVAQOSA-N
Data: 3 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
S-adenosylmethionine synthetase (MAT 1 and MAT 2) (Rattus norvegicus) | BDBM50367305 (CHEMBL1791430) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | 9.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory constant against rat liver Methionine adenosyltransferase I, activity expressed as Ki | J Med Chem 29: 318-22 (1986) BindingDB Entry DOI: 10.7270/Q2DF6RSH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
S-adenosylmethionine synthetase (MAT 1 and MAT 2) (Rattus norvegicus) | BDBM50367305 (CHEMBL1791430) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | 8.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Competitive inhibition of rat methionine adenosyltransferase, activity expressed as Ki | J Med Chem 29: 318-22 (1986) BindingDB Entry DOI: 10.7270/Q2DF6RSH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
S-adenosylmethionine synthetase (MAT 1 and MAT 2) (Rattus norvegicus) | BDBM50367305 (CHEMBL1791430) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | 1.90E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory constant against rat kidney Methionine adenosyltransferase II, activity expressed as Ki | J Med Chem 29: 318-22 (1986) BindingDB Entry DOI: 10.7270/Q2DF6RSH | |||||||||||
More data for this Ligand-Target Pair |