BDBM50367740 CHEMBL1907766

SMILES: CC[C@H](NC(=O)CC)c1nc2c(cccc2c(O)c1C(=O)Nc1nccs1)C(F)(F)F

InChI Key: InChIKey=FLKLCVZAZBAKOJ-LBPRGKRZSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50367740   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclooxygenase (Bos taurus)	BDBM50367740 (CHEMBL1907766) Show SMILES CC[C@H](NC(=O)CC)c1nc2c(cccc2c(O)c1C(=O)Nc1nccs1)C(F)(F)F |r| Show InChI InChI=1S/C20H19F3N4O3S/c1-3-12(25-13(28)4-2)16-14(18(30)27-19-24-8-9-31-19)17(29)10-6-5-7-11(15(10)26-16)20(21,22)23/h5-9,12H,3-4H2,1-2H3,(H,25,28)(H,26,29)(H,24,27,30)/t12-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches Roussel Uclaf Curated by ChEMBL					Assay Description Inhibition of bovine Prostaglandin G/H synthase after oral administration				J Med Chem 31: 1453-62 (1988) BindingDB Entry DOI: 10.7270/Q2JM2B7T
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50367740 (CHEMBL1907766) Show SMILES CC[C@H](NC(=O)CC)c1nc2c(cccc2c(O)c1C(=O)Nc1nccs1)C(F)(F)F |r| Show InChI InChI=1S/C20H19F3N4O3S/c1-3-12(25-13(28)4-2)16-14(18(30)27-19-24-8-9-31-19)17(29)10-6-5-7-11(15(10)26-16)20(21,22)23/h5-9,12H,3-4H2,1-2H3,(H,25,28)(H,26,29)(H,24,27,30)/t12-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches Roussel Uclaf Curated by ChEMBL					Assay Description Inhibition of 5-lipoxygenase from rat peritoneal neutrophils after oral administration				J Med Chem 31: 1453-62 (1988) BindingDB Entry DOI: 10.7270/Q2JM2B7T
					More data for this Ligand-Target Pair