BDBM50368767 CHEMBL4163697

SMILES: Cn1cnc(c1)S(=O)(=O)NCCOc1ccc2CC[C@H](N)[C@H](Cc3cccc(Cl)c3)c2c1

InChI Key: InChIKey=IIACABROFGKJAI-DUULHIFXSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50368767   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycine transporter 1 (Homo sapiens (Human))	BDBM50368767 (CHEMBL4163697) Show SMILES Cn1cnc(c1)S(=O)(=O)NCCOc1ccc2CC[C@H](N)[C@H](Cc3cccc(Cl)c3)c2c1 |r| Show InChI InChI=1S/C38H57N7O14/c1-18(2)13-24(43-37(57)31(21(6)46)45-36(56)25(40-22(7)47)15-23-11-9-8-10-12-23)34(54)42-26(16-29(48)49)33(53)39-20(5)32(52)41-27(17-30(50)51)35(55)44-28(38(58)59)14-19(3)4/h8-12,18-21,24-28,31,46H,13-17H2,1-7H3,(H,39,53)(H,40,47)(H,41,52)(H,42,54)(H,43,57)(H,44,55)(H,45,56)(H,48,49)(H,50,51)(H,58,59)/t20-,21-,24-,25-,26-,27-,28-,31-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Deutschland GmbH & Co. KG Curated by ChEMBL					Assay Description Displacement of [3H]N-Methyl-SSR504734 from human GlyT1c expressed in cell membranes incubated for 1 hr by liquid scintillation spectrometry				J Med Chem 61: 7503-7524 (2018) Article DOI: 10.1021/acs.jmedchem.8b00300 BindingDB Entry DOI: 10.7270/Q2W66P9B
					More data for this Ligand-Target Pair