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SMILES: C[C@@H](COc1ccc(cc1)C1Oc2ccc(O)cc2C(C)=C1c1ccc(F)cc1)N1CC[C@@H](C)C1

InChI Key: InChIKey=YKDMPXQGNUAFHO-PGJZWCTDSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50368869   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Estrogen receptor


(Homo sapiens (Human))		BDBM50368869
PNG
(CHEMBL4167152)
Show SMILES C[C@@H](COc1ccc(cc1)C1Oc2ccc(O)cc2C(C)=C1c1ccc(F)cc1)N1CC[C@@H](C)C1 |r,c:22|
Show InChI InChI=1S/C30H32FNO3/c1-19-14-15-32(17-19)20(2)18-34-26-11-6-23(7-12-26)30-29(22-4-8-24(31)9-5-22)21(3)27-16-25(33)10-13-28(27)35-30/h4-13,16,19-20,30,33H,14-15,17-18H2,1-3H3/t19-,20+,30?/m1/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 0.400n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Induction of ERalpha degradation in human MCF7 cells in phenol red free RPMI medium containing 5% charcoal dextran-treated FBS incubated for 4 hrs by...

J Med Chem 61: 7917-7928 (2018)


Article DOI: 10.1021/acs.jmedchem.8b00921
BindingDB Entry DOI: 10.7270/Q2MP55SC
More data for this
Ligand-Target Pair