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SMILES: OC(O)c1nc2n(cnc2c(=O)[nH]1)C1O[C@@H](COP(O)(O)=O)[C@H](O)[C@@H]1O

InChI Key: InChIKey=LHKRJRIUNHSFGG-RNHMCSNZSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50369231   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Inosine-5'-monophosphate dehydrogenase 2


(Homo sapiens (Human))		BDBM50369231
PNG
(CHEMBL610230)
Show SMILES OC(O)c1nc2n(cnc2c(=O)[nH]1)C1O[C@@H](COP(O)(O)=O)[C@H](O)[C@@H]1O |r|
Show InChI InChI=1S/C11H15N4O10P/c16-5-3(1-24-26(21,22)23)25-10(6(5)17)15-2-12-4-8(15)13-7(11(19)20)14-9(4)18/h2-3,5-6,10-11,16-17,19-20H,1H2,(H,13,14,18)(H2,21,22,23)/t3-,5-,6-,10?/m0/s1
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Article
PubMed
n/an/a 440n/an/an/an/an/an/a



University of Chicago

Curated by ChEMBL


Assay Description
Concentration required for 50% inhibition of human Inosine-5'-monophosphate dehydrogenase 2 using Spectrophotometric assay

J Med Chem 40: 4-8 (1997)


Article DOI: 10.1021/jm960732v
BindingDB Entry DOI: 10.7270/Q2QR4XR8
More data for this
Ligand-Target Pair