BDBM50369531 CHEMBL608900

SMILES: Cn1nc(NC(=O)c2ccccc2)c2cn(C3O[C@H](CO)[C@@H](O)[C@H]3O)c3ncnc1c23

InChI Key: InChIKey=YGBKJDHHNOQVAZ-VBFWCBHKSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50369531   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Human immunodeficiency virus type 1 reverse transcriptase (Human immunodeficiency virus 1)	BDBM50369531 (CHEMBL608900) Show SMILES Cn1nc(NC(=O)c2ccccc2)c2cn(C3O[C@H](CO)[C@@H](O)[C@H]3O)c3ncnc1c23 |r| Show InChI InChI=1S/C20H20N6O5/c1-25-17-13-11(16(24-25)23-19(30)10-5-3-2-4-6-10)7-26(18(13)22-9-21-17)20-15(29)14(28)12(8-27)31-20/h2-7,9,12,14-15,20,27-29H,8H2,1H3,(H,23,24,30)/t12-,14-,15-,20?/m1/s1	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Antiviral activity was evaluated by RT (reverse transcriptase) activity in cells acutely infected with HIV-1				J Med Chem 43: 2457-63 (2000) BindingDB Entry DOI: 10.7270/Q22N52Z2
					More data for this Ligand-Target Pair