BDBM50370124 CHEMBL4160651

SMILES: ONC(=O)c1cccc(OCc2ccc(cc2)C#N)c1

InChI Key: InChIKey=VIBCDPXFBNEQSK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50370124   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sphingomyelin phosphodiesterase (Homo sapiens)	BDBM50370124 (CHEMBL4160651) Show SMILES ONC(=O)c1cccc(OCc2ccc(cc2)C#N)c1 Show InChI InChI=1S/C15H12N2O3/c16-9-11-4-6-12(7-5-11)10-20-14-3-1-2-13(8-14)15(18)17-19/h1-8,19H,10H2,(H,17,18)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.29E+4	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of acid sphingomyelinase in human HuH7 cell lysate using NBD-sphingomyelin as substrate after 30 mins by TLC based fluorescence assay				Eur J Med Chem 151: 389-400 (2018) Article DOI: 10.1016/j.ejmech.2018.03.065 BindingDB Entry DOI: 10.7270/Q21R6T2M
					More data for this Ligand-Target Pair