BDBM50370148 CHEMBL4159268

SMILES: COc1ccc(COc2cccc(c2)C(=O)NO)cc1

InChI Key: InChIKey=PYGNFTFGCFKAKR-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50370148   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sphingomyelin phosphodiesterase (Homo sapiens)	BDBM50370148 (CHEMBL4159268) Show SMILES COc1ccc(COc2cccc(c2)C(=O)NO)cc1 Show InChI InChI=1S/C15H15NO4/c1-19-13-7-5-11(6-8-13)10-20-14-4-2-3-12(9-14)15(17)16-18/h2-9,18H,10H2,1H3,(H,16,17)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.27E+4	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of acid sphingomyelinase in human HuH7 cell lysate using NBD-sphingomyelin as substrate after 30 mins by TLC based fluorescence assay				Eur J Med Chem 151: 389-400 (2018) Article DOI: 10.1016/j.ejmech.2018.03.065 BindingDB Entry DOI: 10.7270/Q21R6T2M
					More data for this Ligand-Target Pair