null

SMILES:

InChI Key: InChIKey=CJCOVJOOLONIPG-ULKLKXEZSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50370167   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin-releasing factor receptor 2 (Homo sapiens (Human))	BDBM50370167 (CHEMBL1794010) Show SMILES Show InChI InChI=1S/C157H263N45O44/c1-23-27-40-92(182-141(232)103(51-59-120(211)212)191-149(240)110(70-81(13)14)198-154(245)123(82(15)16)200-144(235)104(52-60-121(213)214)189-137(228)97(45-37-65-172-157(167)168)186-148(239)108(68-79(9)10)195-150(241)109(69-80(11)12)196-151(242)111(72-90-74-169-76-173-90)192-131(222)91(159)71-89-38-30-29-31-39-89)132(223)174-85(19)127(218)178-96(44-36-64-171-156(165)166)133(224)175-86(20)129(220)181-102(50-58-119(209)210)140(231)188-100(48-56-116(162)206)142(233)193-106(66-77(5)6)146(237)177-88(22)130(221)179-99(47-55-115(161)205)139(230)187-98(46-54-114(160)204)134(225)176-87(21)128(219)180-101-49-57-118(208)170-63-35-33-43-95(185-152(243)112(73-117(163)207)197-153(244)113(75-203)199-143(101)234)136(227)183-94(42-32-34-62-158)138(229)194-107(67-78(7)8)147(238)184-93(41-28-24-2)135(226)190-105(53-61-122(215)216)145(236)202-125(84(18)26-4)155(246)201-124(126(164)217)83(17)25-3/h29-31,38-39,74,76-88,91-113,123-125,203H,23-28,32-37,40-73,75,158-159H2,1-22H3,(H2,160,204)(H2,161,205)(H2,162,206)(H2,163,207)(H2,164,217)(H,169,173)(H,170,208)(H,174,223)(H,175,224)(H,176,225)(H,177,237)(H,178,218)(H,179,221)(H,180,219)(H,181,220)(H,182,232)(H,183,227)(H,184,238)(H,185,243)(H,186,239)(H,187,230)(H,188,231)(H,189,228)(H,190,226)(H,191,240)(H,192,222)(H,193,233)(H,194,229)(H,195,241)(H,196,242)(H,197,244)(H,198,245)(H,199,234)(H,200,235)(H,201,246)(H,202,236)(H,209,210)(H,211,212)(H,213,214)(H,215,216)(H4,165,166,171)(H4,167,168,172)/t83-,84-,85+,86+,87+,88+,91+,92+,93+,94+,95-,96+,97+,98+,99+,100+,101+,102+,103+,104+,105+,106+,107+,108+,109+,110+,111+,112-,113+,123+,124+,125+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Salk Institute Curated by ChEMBL					Assay Description Inhibition of recombinant human corticotropin releasing factor receptor 2 beta (CRF2beta) assayed using nonselective [125I]-labeled agonist [Tyr0,Glu...				J Med Chem 45: 4737-47 (2002) BindingDB Entry DOI: 10.7270/Q2WQ04JR
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50370167 (CHEMBL1794010) Show SMILES Show InChI InChI=1S/C157H263N45O44/c1-23-27-40-92(182-141(232)103(51-59-120(211)212)191-149(240)110(70-81(13)14)198-154(245)123(82(15)16)200-144(235)104(52-60-121(213)214)189-137(228)97(45-37-65-172-157(167)168)186-148(239)108(68-79(9)10)195-150(241)109(69-80(11)12)196-151(242)111(72-90-74-169-76-173-90)192-131(222)91(159)71-89-38-30-29-31-39-89)132(223)174-85(19)127(218)178-96(44-36-64-171-156(165)166)133(224)175-86(20)129(220)181-102(50-58-119(209)210)140(231)188-100(48-56-116(162)206)142(233)193-106(66-77(5)6)146(237)177-88(22)130(221)179-99(47-55-115(161)205)139(230)187-98(46-54-114(160)204)134(225)176-87(21)128(219)180-101-49-57-118(208)170-63-35-33-43-95(185-152(243)112(73-117(163)207)197-153(244)113(75-203)199-143(101)234)136(227)183-94(42-32-34-62-158)138(229)194-107(67-78(7)8)147(238)184-93(41-28-24-2)135(226)190-105(53-61-122(215)216)145(236)202-125(84(18)26-4)155(246)201-124(126(164)217)83(17)25-3/h29-31,38-39,74,76-88,91-113,123-125,203H,23-28,32-37,40-73,75,158-159H2,1-22H3,(H2,160,204)(H2,161,205)(H2,162,206)(H2,163,207)(H2,164,217)(H,169,173)(H,170,208)(H,174,223)(H,175,224)(H,176,225)(H,177,237)(H,178,218)(H,179,221)(H,180,219)(H,181,220)(H,182,232)(H,183,227)(H,184,238)(H,185,243)(H,186,239)(H,187,230)(H,188,231)(H,189,228)(H,190,226)(H,191,240)(H,192,222)(H,193,233)(H,194,229)(H,195,241)(H,196,242)(H,197,244)(H,198,245)(H,199,234)(H,200,235)(H,201,246)(H,202,236)(H,209,210)(H,211,212)(H,213,214)(H,215,216)(H4,165,166,171)(H4,167,168,172)/t83-,84-,85+,86+,87+,88+,91+,92+,93+,94+,95-,96+,97+,98+,99+,100+,101+,102+,103+,104+,105+,106+,107+,108+,109+,110+,111+,112-,113+,123+,124+,125+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>100	n/a	n/a	n/a	n/a	n/a	n/a
Salk Institute Curated by ChEMBL					Assay Description Inhibition of recombinant corticotropin releasing factor receptor 1 assayed using nonselective [125I]-labeled agonist [Tyr0,Glu1,Nle17]-sauvagine				J Med Chem 45: 4737-47 (2002) BindingDB Entry DOI: 10.7270/Q2WQ04JR
					More data for this Ligand-Target Pair