null

SMILES: OC[C@H]1N[C@H](C(O)[C@H]1O)c1c(F)[nH]c2c1nc[nH]c2=O

InChI Key: InChIKey=MIRJLTROAUGHCB-SZYGJNCVSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50370251   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Purine nucleoside phosphorylase (Homo sapiens (Human))	BDBM50370251 (CHEMBL542455) Show SMILES OC[C@H]1N[C@H](C(O)[C@H]1O)c1c(F)[nH]c2c1nc[nH]c2=O |r| Show InChI InChI=1S/C11H13FN4O4/c12-10-4(5-7(16-10)11(20)14-2-13-5)6-9(19)8(18)3(1-17)15-6/h2-3,6,8-9,15-19H,1H2,(H,13,14,20)/t3-,6+,8+,9?/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.390	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Industrial Research Limited Curated by ChEMBL					Assay Description Equilibrium dissociation constant determined against human purine nucleoside phosphorylase (PNP) after slow-onset inhibition				J Med Chem 46: 3412-23 (2003) Article DOI: 10.1021/jm030145r BindingDB Entry DOI: 10.7270/Q2X92C29
					More data for this Ligand-Target Pair
Purine nucleoside phosphorylase (Homo sapiens (Human))	BDBM50370251 (CHEMBL542455) Show SMILES OC[C@H]1N[C@H](C(O)[C@H]1O)c1c(F)[nH]c2c1nc[nH]c2=O |r| Show InChI InChI=1S/C11H13FN4O4/c12-10-4(5-7(16-10)11(20)14-2-13-5)6-9(19)8(18)3(1-17)15-6/h2-3,6,8-9,15-19H,1H2,(H,13,14,20)/t3-,6+,8+,9?/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Industrial Research Limited Curated by ChEMBL					Assay Description Inhibition of human purine nucleoside phosphorylase; Initial rate.				J Med Chem 46: 3412-23 (2003) Article DOI: 10.1021/jm030145r BindingDB Entry DOI: 10.7270/Q2X92C29
					More data for this Ligand-Target Pair