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SMILES: CCC(CC)N1CCN(CC1)C(=O)CCC(=O)c1ccc(OC)c(F)c1

InChI Key: InChIKey=OFILBGRLJTWLGG-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50370330   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histamine H3 receptor


(Homo sapiens (Human))		BDBM50370330
PNG
(CHEMBL1202893)
Show SMILES CCC(CC)N1CCN(CC1)C(=O)CCC(=O)c1ccc(OC)c(F)c1
Show InChI InChI=1S/C20H29FN2O3/c1-4-16(5-2)22-10-12-23(13-11-22)20(25)9-7-18(24)15-6-8-19(26-3)17(21)14-15/h6,8,14,16H,4-5,7,9-13H2,1-3H3
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Similars
Article
PubMed
 0.430n/an/an/an/an/an/an/an/a



Novo Nordisk A/S

Curated by ChEMBL


Assay Description
Antagonist potency against human histamine H3 receptor expressed in CHO cells was determined by GTPgamma-S-assay

J Med Chem 47: 2833-8 (2004)


Article DOI: 10.1021/jm031028z
BindingDB Entry DOI: 10.7270/Q2T154CW
More data for this
Ligand-Target Pair