BDBM50370390 CHEMBL1790808

SMILES: [#6]-[#6]-[#6@@H](-[#6])-[#6@H](\[#7]=[#6](/[#7])-[#7])-[#6](=O)-[#7]-[#6]-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccc(cc1)C#Cc1ccccc1)-[#6](=O)-[#8]-[#6]

InChI Key: InChIKey=XGGOZVAZONWKNW-OUOWLKGYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50370390   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Interleukin-2 receptor alpha chain (Mus musculus)	BDBM50370390 (CHEMBL1790808) Show SMILES [#6]-[#6]-[#6@@H](-[#6])-[#6@H](\[#7]=[#6](/[#7])-[#7])-[#6](=O)-[#7]-[#6]-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccc(cc1)C#Cc1ccccc1)-[#6](=O)-[#8]-[#6] Show InChI InChI=1S/C27H33N5O4/c1-4-18(2)24(32-27(28)29)25(34)30-17-23(33)31-22(26(35)36-3)16-21-14-12-20(13-15-21)11-10-19-8-6-5-7-9-19/h5-9,12-15,18,22,24H,4,16-17H2,1-3H3,(H,30,34)(H,31,33)(H4,28,29,32)/t18-,22+,24+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sunesis Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of mouse interleukin-2 alpha receptor by ELISA				J Med Chem 47: 3111-30 (2004) Article DOI: 10.1021/jm049967u BindingDB Entry DOI: 10.7270/Q2TQ6280
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