BDBM50370591 CEFPIROME::Cefrom

SMILES: CO\N=C(/C(=O)N[C@@H]1[C@H]2SCC(C[n+]3cccc4CCCc34)=C(N2C1=O)C([O-])=O)c1csc(N)n1

InChI Key: InChIKey=DKOQGJHPHLTOJR-VWDXTOPWSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50370591   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Oligopeptide transporter, kidney isoform (Rattus norvegicus)	BDBM50370591 (CEFPIROME | Cefrom) Show SMILES CO\N=C(/C(=O)N[C@@H]1[C@H]2SCC(C[n+]3cccc4CCCc34)=C(N2C1=O)C([O-])=O)c1csc(N)n1 |r,c:23| Show InChI InChI=1S/C22H22N6O5S2/c1-33-26-15(13-10-35-22(23)24-13)18(29)25-16-19(30)28-17(21(31)32)12(9-34-20(16)28)8-27-7-3-5-11-4-2-6-14(11)27/h3,5,7,10,16,20H,2,4,6,8-9H2,1H3,(H3-,23,24,25,29,31,32)/b26-15-/t16-,20+/m0/s1	PDB Reactome pathway KEGG GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	9.50E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Biozentrum of the Martin-Luther-University Halle-Wittenberg Curated by ChEMBL					Assay Description TP_TRANSPORTER: inhibition of Gly-Sar uptake (pH6.0) in SKPT cells				Eur J Pharm Biopharm 59: 17-24 (2004) Article DOI: 10.1016/j.ejpb.2004.07.008 BindingDB Entry DOI: 10.7270/Q2TT4S7H
					More data for this Ligand-Target Pair
Oligopeptide transporter small intestine isoform (Homo sapiens (Human))	BDBM50370591 (CEFPIROME | Cefrom) Show SMILES CO\N=C(/C(=O)N[C@@H]1[C@H]2SCC(C[n+]3cccc4CCCc34)=C(N2C1=O)C([O-])=O)c1csc(N)n1 |r,c:23| Show InChI InChI=1S/C22H22N6O5S2/c1-33-26-15(13-10-35-22(23)24-13)18(29)25-16-19(30)28-17(21(31)32)12(9-34-20(16)28)8-27-7-3-5-11-4-2-6-14(11)27/h3,5,7,10,16,20H,2,4,6,8-9H2,1H3,(H3-,23,24,25,29,31,32)/b26-15-/t16-,20+/m0/s1	PDB Reactome pathway KEGG DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	>3.00E+7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Martin-Luther-University Halle-Wittenberg Curated by ChEMBL					Assay Description Binding affinity against membrane transport protein PEPT1 in human Caco-2 cells				J Med Chem 48: 4410-9 (2005) Article DOI: 10.1021/jm048982w BindingDB Entry DOI: 10.7270/Q2Q24116
					More data for this Ligand-Target Pair
Oligopeptide transporter small intestine isoform (Homo sapiens (Human))	BDBM50370591 (CEFPIROME | Cefrom) Show SMILES CO\N=C(/C(=O)N[C@@H]1[C@H]2SCC(C[n+]3cccc4CCCc34)=C(N2C1=O)C([O-])=O)c1csc(N)n1 |r,c:23| Show InChI InChI=1S/C22H22N6O5S2/c1-33-26-15(13-10-35-22(23)24-13)18(29)25-16-19(30)28-17(21(31)32)12(9-34-20(16)28)8-27-7-3-5-11-4-2-6-14(11)27/h3,5,7,10,16,20H,2,4,6,8-9H2,1H3,(H3-,23,24,25,29,31,32)/b26-15-/t16-,20+/m0/s1	PDB Reactome pathway KEGG DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	>3.00E+7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Biozentrum of the Martin-Luther-University Halle-Wittenberg Curated by ChEMBL					Assay Description TP_TRANSPORTER: inhibition of Gly-Sar uptake (pH6.0) in Caco-2 cells				Eur J Pharm Biopharm 59: 17-24 (2004) Article DOI: 10.1016/j.ejpb.2004.07.008 BindingDB Entry DOI: 10.7270/Q2TT4S7H
					More data for this Ligand-Target Pair