BDBM50371151 CHEMBL242457

SMILES: Cc1c(Cc2c(Cl)cccc2Cl)c(=O)ccn1CCc1ccc(cc1)-c1c[nH]c(CNC(=O)Nc2ncc[nH]2)n1

InChI Key: InChIKey=WDRFGKPBTCQNGZ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50371151   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Enoyl-ACP Reductase (FabK) (Streptococcus pneumoniae)	BDBM50371151 (CHEMBL242457) Show SMILES Cc1c(Cc2c(Cl)cccc2Cl)c(=O)ccn1CCc1ccc(cc1)-c1c[nH]c(CNC(=O)Nc2ncc[nH]2)n1 Show InChI InChI=1S/C29H27Cl2N7O2/c1-18-21(15-22-23(30)3-2-4-24(22)31)26(39)10-14-38(18)13-9-19-5-7-20(8-6-19)25-16-34-27(36-25)17-35-29(40)37-28-32-11-12-33-28/h2-8,10-12,14,16H,9,13,15,17H2,1H3,(H,34,36)(H3,32,33,35,37,40)	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Meiji Seika Kaisha, Ltd. Curated by ChEMBL					Assay Description Inhibition of Streptococcus pneumoniae FabK				J Med Chem 50: 4710-20 (2007) Article DOI: 10.1021/jm0705354 BindingDB Entry DOI: 10.7270/Q2NZ88GS
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