BDBM50371246 CHEMBL250444

SMILES: Cc1cccc(NC(=O)c2ccc(o2)-c2ccc(cc2)S(C)(=O)=O)c1

InChI Key: InChIKey=IAVGDMHOLZCTBP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50371246   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium channel protein type X alpha subunit (Mus musculus)	BDBM50371246 (CHEMBL250444) Show SMILES Cc1cccc(NC(=O)c2ccc(o2)-c2ccc(cc2)S(C)(=O)=O)c1 Show InChI InChI=1S/C19H17NO4S/c1-13-4-3-5-15(12-13)20-19(21)18-11-10-17(24-18)14-6-8-16(9-7-14)25(2,22)23/h3-12H,1-2H3,(H,20,21)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of mouse recombinant Nav 1.8 channel expressed in HEK293 cells by isotopic efflux assay				J Med Chem 51: 407-16 (2008) Article DOI: 10.1021/jm070637u BindingDB Entry DOI: 10.7270/Q2KK9CN7
					More data for this Ligand-Target Pair