Found 5 hits for monomerid = 50371304 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Sodium-dependent serotonin transporter
(Rattus norvegicus (rat)) | BDBM50371304
(CHEMBL270165)Show SMILES CNCc1cc(ccc1Oc1ccc(SC)cc1)C(=O)N1CCN(CC1)C1CC1 Show InChI InChI=1S/C23H29N3O2S/c1-24-16-18-15-17(23(27)26-13-11-25(12-14-26)19-4-5-19)3-10-22(18)28-20-6-8-21(29-2)9-7-20/h3,6-10,15,19,24H,4-5,11-14,16H2,1-2H3 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research& Development L.L.C.
Curated by ChEMBL
| Assay Description
Inhibition of rat SERT |
Bioorg Med Chem Lett 18: 39-43 (2008)
Article DOI: 10.1016/j.bmcl.2007.11.016
BindingDB Entry DOI: 10.7270/Q2R49RMD |
More data for this
Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50371304
(CHEMBL270165)Show SMILES CNCc1cc(ccc1Oc1ccc(SC)cc1)C(=O)N1CCN(CC1)C1CC1 Show InChI InChI=1S/C23H29N3O2S/c1-24-16-18-15-17(23(27)26-13-11-25(12-14-26)19-4-5-19)3-10-22(18)28-20-6-8-21(29-2)9-7-20/h3,6-10,15,19,24H,4-5,11-14,16H2,1-2H3 | PDB
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research& Development L.L.C.
Curated by ChEMBL
| Assay Description
Inhibition of human SERT |
Bioorg Med Chem Lett 18: 39-43 (2008)
Article DOI: 10.1016/j.bmcl.2007.11.016
BindingDB Entry DOI: 10.7270/Q2R49RMD |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50371304
(CHEMBL270165)Show SMILES CNCc1cc(ccc1Oc1ccc(SC)cc1)C(=O)N1CCN(CC1)C1CC1 Show InChI InChI=1S/C23H29N3O2S/c1-24-16-18-15-17(23(27)26-13-11-25(12-14-26)19-4-5-19)3-10-22(18)28-20-6-8-21(29-2)9-7-20/h3,6-10,15,19,24H,4-5,11-14,16H2,1-2H3 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 29 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research& Development L.L.C.
Curated by ChEMBL
| Assay Description
Inhibition of human histamine H3 receptor |
Bioorg Med Chem Lett 18: 39-43 (2008)
Article DOI: 10.1016/j.bmcl.2007.11.016
BindingDB Entry DOI: 10.7270/Q2R49RMD |
More data for this
Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50371304
(CHEMBL270165)Show SMILES CNCc1cc(ccc1Oc1ccc(SC)cc1)C(=O)N1CCN(CC1)C1CC1 Show InChI InChI=1S/C23H29N3O2S/c1-24-16-18-15-17(23(27)26-13-11-25(12-14-26)19-4-5-19)3-10-22(18)28-20-6-8-21(29-2)9-7-20/h3,6-10,15,19,24H,4-5,11-14,16H2,1-2H3 | Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 3.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research& Development L.L.C.
Curated by ChEMBL
| Assay Description
Binding affinity to human NET |
Bioorg Med Chem Lett 18: 39-43 (2008)
Article DOI: 10.1016/j.bmcl.2007.11.016
BindingDB Entry DOI: 10.7270/Q2R49RMD |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50371304
(CHEMBL270165)Show SMILES CNCc1cc(ccc1Oc1ccc(SC)cc1)C(=O)N1CCN(CC1)C1CC1 Show InChI InChI=1S/C23H29N3O2S/c1-24-16-18-15-17(23(27)26-13-11-25(12-14-26)19-4-5-19)3-10-22(18)28-20-6-8-21(29-2)9-7-20/h3,6-10,15,19,24H,4-5,11-14,16H2,1-2H3 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 8.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research& Development L.L.C.
Curated by ChEMBL
| Assay Description
Binding affinity to human DAT |
Bioorg Med Chem Lett 18: 39-43 (2008)
Article DOI: 10.1016/j.bmcl.2007.11.016
BindingDB Entry DOI: 10.7270/Q2R49RMD |
More data for this
Ligand-Target Pair | |
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